NMR Spectroscopist

Job title:

NMR Spectroscopist

Company

GlaxoSmithKline

Job description

We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.We embrace modern work practises; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work.Discover more about our company wide benefits and life at GSK on our webpageNMR SpectroscopistWe currently have a vacancy in our analytical group for a spectroscopist focussing on solution-state NMR spectroscopy, also working in vibrational spectroscopy (IR, Raman, etc). This is an exciting opportunity for an enthusiastic individual to join a spectroscopy-focussed team within a multi-disciplinary analytical department, delivering expert solution-state NMR and vibrational spectroscopy support to a range of projects from discovery phases through development phases to marketing. Applications in small molecules, oligonucleotides, protein therapeutics and drug products will all form part of this exciting role.Working in a flexible team which spans solution-state NMR, solid-state NMR and vibrational spectroscopy, the successful candidate will undertake NMR analysis, as well as vibrational spectroscopy, supporting problem solving and product development for multiple projects with diverse challenges. This may include structure elucidation, development and validation of quantitative methodologies, mixture analysis, multinuclear NMR, IR and Raman. The successful candidate will also work alongside other multi-faceted scientists as part of cross-functional project teams and will work with a high level of autonomy and accountability, contributing to regulatory submissions and overseeing the completion of work packages to deadlines.Primary responsibilities and duties of this role, under the guidance of a team leader, include:

• To work as part of a spectroscopy team within a wider analytical department, to provide NMR and vibrational spectroscopy analysis and interpretation for drug substances and drug products through project lifecycles from Discovery through Development to Marketing
• To suggest, develop and apply innovative experimental approaches, evaluate results and provide reports on work performed
• To evaluate, introduce and apply new methodology, workflows and technology in solution NMR, contributing to the strategic development of the spectroscopy group
• To actively work in global, multi-disciplinary project teams including analysts, chemists, formulators and others to solve problems by the most effective route, using a knowledge of other key analytical techniques, including mass spectrometry, vibrational spectroscopy, computer modelling and others
• To troubleshoot experimental and instrumental problems
• To comply with the requirements of Quality, Safety and GSK policies and procedures and ensure that GSK intellectual property is protected
• To contribute as part of a diverse and dynamic department to delivery of all aspects of work contributing to progression of the portfolio, including critical digital and data-based objectives

Essential Qualifications/Experience:

• BSc or PhD (or equivalents) in Chemistry or Physical Chemistry or related subject, preferably in an NMR spectroscopy-related discipline
• Experience in the application of NMR in the study of small molecule organic materials
• Understanding and knowledge of state-of-the-art NMR spectroscopy, NMR techniques and instrumentation and the wide range of NMR applications in the pharmaceutical (or related) industry, potentially with experience developing and implementing novel solution-state NMR methodology in this area
• Self-motivated flexible approach with good organizational/project management skills, strong ability to communicate in a scientific manner, good interpersonal skills, ability to work independently and problem solve with a track record of generating high quality data and reports
• Demonstrated ability to proactively build networks and relationships that instil confidence, trust and teamwork.

Preferred Qualifications/Experience:

• Experience of the use of NMR in structure elucidation of small molecule organic materials and/or oligonucleotides, and in developing, novel methodology, ideally in the pharmaceutical (or related) industry,
• Experience of analysis of small molecules/ polymorphs by vibrational spectroscopy (IR and Raman) techniques
• Experience in regulated GxP laboratory working, including an understanding or experience of method validation requirements
• Knowledge and understanding of Digital, Data and Analytics principles, tools and approaches, and ideally experience of implementing such tools and workflows to deliver efficient ways of working
• Knowledge of other structural analysis techniques and the way to use these techniques complementarily, e.g. solid-state NMR, XRPD, single crystal X-ray diffraction, mass spectrometry, etc
• Knowledge of other structural analysis techniques and the way to use these techniques complementarily, e.g. vibrational spectroscopy (IR, Raman), solid-state NMR, XRPD, single crystal X-ray diffraction, mass spectrometry, etc

Closing Date for Applications – Wednesday 24th October 2024Please take a copy of the Job Description, as this will not be available post closure of the advert.
When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.GSK R&DAt GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people over the next 10 years. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease. Science and technology are coming together in a way they never have before, and we have strong tech-enabled capabilities that allow us to build a deeper understanding of the patient, human biology and disease mechanisms, and transform medical discovery. We are revolutionising the way we do R&D. We’re uniting science, technology and talent to get ahead of disease together.Find out more: .Why GSK?Uniting science, technology and talent to get ahead of disease together.GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class*(*US only).We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on or 0808 234 4391.Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a UK Recruitment FAQ guide. Click the and scroll to the Careers Section where you will find answers to multiple questions we receive .As you apply, we will ask you to share some personal information which is entirely voluntary. We want to have an opportunity to consider a diverse pool of qualified candidates and this information will assist us in meeting that objective and in understanding how well we are doing against our inclusion and diversity ambitions. We would really appreciate it if you could take a few moments to complete it. 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Expected salary

Location

Stevenage, Hertfordshire

Job date

Sat, 12 Oct 2024 02:13:49 GMT

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