Software Developer, Bioinformatics

Job title:

Software Developer, Bioinformatics

Company

DNA Script

Job description

DNA Script is a leading company in manufacturing de novo synthetic nucleic acids using enzymatic DNA synthesis (EDS) technology. The company aims at accelerating innovation in life science and technology through the decentralization of rapid, on demand and high-quality DNA synthesis. DNA Script’s approach leverages nature’s billions of years of evolution in synthesizing DNA to set a new standard for customizing nucleic acid synthesis thus accelerating discovery in genetics, genomics, and synthetic biology. Discovery disciplines with profound impacts upon humanity such as biopharma, translational genetics and even molecular information storage all start with synthetic DNA. The company has recently initiated the commercialization of its first EDS powered platform, the SYNTAX system.To date, DNA Script has raised over $315M of financing, with leading investors such as Coatue Management, Fidelity Management and Research, Catalio Capital Management, Casdin Capital, LSP, Bpifrance Large Ventures, Danaher, Illumina Ventures, Agilent, Merck Ventures, Sofinnova Partners, Kurma Partners and Eurazeo.DNA Script also partners on technology and product development with leading organizations such as DARPA, IARPA, Moderna Therapeutics, GE Research, Illumina, the Broad Institute, Harvard University, Institut Pasteur and the French Department of Defense.DNA Script has its research and manufacturing facilities headquartered in Paris, France, and is in the process of expanding its commercial and development teams in South San Francisco.Job DescriptionDNA ScriptDNA Script is a leading company in the production of nucleic acids for genomic, synthetic biology and biopharmaceutical applications.Our clean, efficient Enzymatic DNA Synthesis (EDS) technology, implemented on a benchtop instrument (the SYNTAX), accelerates innovation in life science and biotechnology through the decentralization of rapid, on demand and high quality DNA synthesis.Our approach builds upon nature’s billions of years of evolution in enzymatically synthesizing DNA, setting new standards for assembling nucleic acids to accelerate scientific discovery and DNA/RNA production in disciplines with profound impacts upon humanity.DNA Script has a broad stable of high quality investors and is capitalized to continue its progress to full commercialization of the technology and products. We are building an organization across our two sites, in Paris and San Francisco, with the talent, skills and attitude to achieve our mission: to unlock the power of “DNA-write”.This is an opportunity for a dynamic individual to join an international and highly skilled team, and to make significant contributions to commercializing a technology with far-reaching potential across the biological sciences and beyond.The RoleDNA Script is actively searching for a software developer, Bioinformatics to join a small team providing bioinformatic support to the whole company.The ideal candidate should be enthusiastic and passionate about bioinformatics and related technologies. We are looking for a team player who can rapidly adapt to challenges and interact with different teams as new projects arise. This position would be an excellent match for someone who is comfortable working with both biologists and developers to translate biological data into actionable insights.We have many different teams within DNA Script who have bioinformatic requirements, and this role will include assisting in both the rapid turnaround of biological questions into insight, as well as running and maintaining already established pipelines and tools. Thus, the ability to juggle multiple projects, both short-term and long-term, is crucial.This is an opportunity to join a rapidly growing company and to have a large impact on developing a technology that will have far-reaching impact across biological sciences.Main Responsibilities

• Be in charge of the analysis of NGS and other forms of sequencing data
• Development and maintain of APIs and graphical user interfaces (GUIs) for querying database content
• Design and implement relational databases
• Participate in the development of smart designs to facilitate synthesis and assembly of oligonucleotides
• Creating dashboards for data visualization and analysis
• Participate in the development and improvement of the bioinformatics side of commercial products
• Ensure consolidation, traceability and reliability of generated data and algorithms
• Operationally manage activities required to achieve key objectives linked to strategic partnerships
• Ensure comprehensive, clear and concise reporting of your activities
• Promote inter-teams collaboration
• Promote good coding practices

Qualifications and Education Requirements

• Either a MSc degree in bioinformatics with at least 2 years’ experience of working in a related field
• Or a PhD in a related field (bioinformatics, computational biology)
• Direct experience working with NGS data
• Proficient in Python programming
• Experience in developing and maintaining bioinformatics tools, including databases, APIs, and graphical user interfaces (GUIs)
• Experience in developing interactive tools using technologies such as Flask and/or Shiny
• Comfortable in working to a high standard both independently and as part of a team
• Curious and analytical, with a proven ability to learn quickly
• Proficient in English and a basic level of French

Preferred Skills and Abilities

• Experience in using workflow languages (snakemake, Nextflow) to run pipelines
• Experience working in a cloud environment (e.g. AWS)
• Machine learning / Statistics
• Competence in working on a Linux command line
• Parallelization of computations on High Throughput Computing (HTC) systems.
• Experience with Docker/Singularity is a plus

Recruitment Process

• Initial screening with the hiring manager n+1
• Second screening with the n+2 of the candidate
• Day interview at the office with the manager, cofounders, HR and the rest of the team members

Expected salary

Location

Le Kremlin-Bicêtre, Val-de-Marne

Job date

Wed, 02 Oct 2024 05:44:04 GMT

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